26 Sep 2016
Author Archives: Jean Gervais
MY STORY IS STRAIGHT AND TO THE POINT… MY NAME IS BIG ROB – BORN AND RAISED HERE IN P.S. IN 1998 ‘I’ OPENED THE FIRST N.Y.P.D. NEW YORK PIZZA DELIVERY DOWNTOWN PALM SPRINGS, 3 YEARS LATER I BOUGHT A SECOND STORE IN PALM DESERT… THEN IN 2008 I STARTED HAVING UNCONTROLLABLE GRAN MAL SEIZURES… I HAVE A SITE THAT EXPLAINES THE WHOLE STORY IN DETAIL IF YOU GO TO “EPILEPSYINFO4U.COM” AND UNDER ‘ROB’S STORY’ YOU CAN READ THE WHOLE BUT SHORT STORY ABOUT MY FAMILY HISTORY AND THE SEIZURES… WHAT I AM DOING HERE WITH ‘GO FUND ME’ IS TRYING TO RAISE MONIES SO I CAN GET BACK INTO THE PIZZA BUSINESS, I HAVE BEEN SITTING FOR 7 YEARS NOW AND FINALLY WE HAVE IT UNDER CONTROL, NOW 7 MONTHS SEIZURE FREE THANKS TO THE GREATEST DOCTOR I HAVE EVER MET – DOCTOR LUTHRA – MY NEUROLOGIST!!! PLUS I HAVE MET 3 OTHER PEOPLE HE HAS CURED… I BELONG IN THE KITCHEN MAKING PIZZA’S(NOT SITTING ON A COUCH) ANYONE WHO KNOWS ME CAN VOUGE FOR THAT!!! I AM ASKING FOR YOUR HELP AND WITH THE HELP OF YOUR FRIENDS & FAMILY TO SPREAD THE WORD AND HELP RAISE THESE FUND$ SO I CAN OPEN A BIG ROB’S ORIGINAL NYPD PIZZA WITH A CLEAN AND SAFE ENVIORNMENT SO YOU CAN COME AND ENJOY THAT HOT FRESH TASTY CHEEZY PIZZA AGAIN!!! THANK YOU… BIG ROB…
30 Nov 2015
Team”Shake n Bake” Walk 2015
Our 3rd walk for Epilepsy Awareness…
We will be passing out Purple Hand Made Slide Bracelets. (made by Rob)
We will be Walking Downtown Palm Springs, Ca.
We’ll meet at the Old Staples Bldg on S Indian Ave.
Walk will begin at Parking Lot, Pictures taken along Walk, and proceed N on Indian Ave to Amado Rd, Head west to N Palm Canyon, Then South back to parking lot for Group Photo.
Show your Support Wear Purple.
Wear comfortable shoes.
ALL ARE INVITED TO JOIN US.
05 Nov 2015
Epilepsy Lifeline and Support Series! Meet others with epilepsy and their families at our first group meeting outside of Simple Simon’s in Riverside the 2nd Tuesday of each month at 11 am (first meeting next Tuesday!!!)
Special thanks to our speakers–Drs. Diane Stein and Thomas Minahan, sponsors, City of Riverside, CA – City Government, IEHP, and Molina Healthcare, and all our participants. It was so good to know that everyone was learning something new that day.
07 Oct 2015
Seizure-related respiratory dysfunction may play a critical role in the pathophysiology of sudden unexpected death in epilepsy (SUDEP). In the majority of observed SUDEP cases, there is some evidence of breathing difficulty prior to death. In addition, simultaneous recording of respiratory function in patients undergoing video-EEG monitoring has shown that abnormalities, such as hypoxemia, apnea, and hypercarbia, are commonly seen following seizures.
How seizures affect respiration is not well understood. While brainstem structures are necessary for breathing, cortical structures, especially in the frontal and temporal lobes, may exert significant influence. These cortical regions are also common sites for seizure initiation or propagation, suggesting a possible anatomical link between seizures and breathing dysfunction.
One Study on How Breathing is Effected
In a recent study by Dlouhy and colleagues, the authors examined the effects of seizures and direct stimulation of multiple cortical sites on breathing in three patients undergoing invasive EEG monitoring for epilepsy or tumor surgery. They found:
In one patient, seizures originating in the right frontal lobe caused transient apnea within one second of propagation to the left amygdala.
Electrical stimulation of the left amygdala, but not other sites in the frontal and temporal cortex, led to apnea and hypoxemia.
Similar results were seen in the other two patients, one with right amygdala stimulation and another with left amygdala stimulation.
None of the patients reported shortness of breath or discomfort during stimulation; they were entirely unaware of their breathing difficulty.
These results suggest that the amygdala may play a critical role in modulation of respiration in humans and that disruption of its normal function by seizures can cause breathing abnormalities. It is unknown if these breathing abnormalities are significant enough to cause SUDEP in some cases or whether seizure spread to other critical brain areas or environmental factors, such as prone position, are necessary components in the fatal cascade.
Further studies, including in animal models of seizures and SUDEP, are needed to understand the neurons and pathways involved in amygdala-mediated respiratory control to identify potential targets for intervention to limit the impact of seizures on breathing and potentially reduce SUDEP risk.
Authored by: Daniel Friedman MD | SUDEP Editor on 9/2015
24 Sep 2015